Me and a friend are setting up a co-living business catering for short-term stays by digital nomads, and one of the many questions we're trying to answer is where in the world is the best place to site it.
(We also have a ton of other questions, and it would be super useful if anyone cared to help answer them by spending 3 mins on this quick survey: https://theintro.typeform.com/to/DUSbNl5v)
Before realizing that for me at that stage in my life the best place for me ironically was the country where I started, just in a bigger city with a good metro system.
If you wanna determine this you'd be best off constructing a matrix of priority systems (weather, cost of living, language, broad cultural region a la northern european, southern european/latin, east asian, latin american, etc), nature in the area, etc) and make a tool for an individual to rank their priorities in terms of categories/factors, then rank the options _within_ each of those categories/factors, and then try to score the results for them. But even then, people often don't know what they want or care about until they've experienced a variety of places.